1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Drug Metabolite

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P3146
    FTISADTSK
    FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM).
    FTISADTSK
  • HY-131479A
    Threo-dihydrobupropion
    Threo-dihydrobupropion is a major metabolite of Bupropion, formed via oxidation and reduction exhibit pharmacological activity. Bupropion, a dual dopamine-norepinephrine uptake inhibitor and a nicotine receptor antagonist, is widely used in the management of depression and as a smoking cessation aid.
    Threo-dihydrobupropion
  • HY-144150S
    Pelubiprofen impurity 2-13C2,d6
    Pelubiprofen impurity 2-13C2,d6 is the 13C- and deuterium labeled Pelubiprofen impurity 2.
    Pelubiprofen impurity 2-<sup>13</sup>C<sub>2</sub>,d<sub>6</sub>
  • HY-W686186
    Prasugrel hydroxy thiolactone
    Prasugrel hydroxy thiolactone (compound M18) is a metabolite of Prasugrel (HY-15284). Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits Adenosine 5'-diphosphate (ADP, HY-W010918)-induced platelet aggregation.
    Prasugrel hydroxy thiolactone
  • HY-124414R
    4'-Hydroxytamoxifen (Standard)
    4'-Hydroxytamoxifen (Standard) is the analytical standard of 4'-Hydroxytamoxifen. This product is intended for research and analytical applications. 4'-Hydroxytamoxifen is a metabolite of Tamoxifen. 4'-Hydroxytamoxifen shows higher affinity for the ER than Tamoxifen. 4'-Hydroxytamoxifen induces a non-apoptotic cytotoxic effect in human endometrial adenocarcinoma cells.
    4'-Hydroxytamoxifen (Standard)
  • HY-135328S
    Norverapamil-d7
    Norverapamil-d7 is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
    Norverapamil-d<sub>7</sub>
  • HY-G0017A
    N-Desmethyl imatinib mesylate
    N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR.
    N-Desmethyl imatinib mesylate
  • HY-107830R
    Methyl cholate (Standard)
    Methyl cholate (Standard) is the analytical standard of Methyl cholate. This product is intended for research and analytical applications. Methyl Cholate is methyl ester form of Cholic acid. Cholic acid is one of the major bile acids produced by the liver, where it is synthesized from cholesterol[1].
    Methyl cholate (Standard)
  • HY-W699907
    Pantoprazole sulfide-d8
    Pantoprazole sulfide-d8 is the deuterium labeled Pantoprazole sulfide (HY-W016033). Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor.
    Pantoprazole sulfide-d<sub>8</sub>
  • HY-135359R
    RP 48497 (Standard)
    Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes.
    RP 48497 (Standard)
  • HY-157690
    19(S),20(R)-EDP
    19(S),20(R)-EDP is an epoxidized metabolite of docosahexaenoic acid (HY-B2167).
    19(S),20(R)-EDP
  • HY-142122R
    Imipramine N-oxide (Standard)
    Imipramine N-oxide (Standard) is the analytical standard of Imipramine N-oxide. This product is intended for research and analytical applications. Imipramine N-oxide is the metabolite of Imipramine. Imipramine is a tertiary amine tricyclic antidepressant[1][2].
    Imipramine N-oxide (Standard)
  • HY-17528R
    Cyhalofop (Standard)
    Cyhalofop (Standard) is the analytical standard of Cyhalofop. This product is intended for research and analytical applications. Cyhalofop (Cyhalofop acid), the primary metabolite of Cyhalofop-butyl (HY-B0861) in susceptible grasses, is the herbicidally active metabolite. Cyhalofop-butyl is an aryloxyphenoxypropionate post-emergence herbicide widely used around the world in agriculture.
    Cyhalofop (Standard)
  • HY-W770677
    9-Carboxymethoxymethylguanine-13C2,15N
    9-Carboxymethoxymethylguanine-13C2,15N is the 13C- and 15N-labeled 9-Carboxymethoxymethylguanine (HY-137181). 9-Carboxymethoxymethylguanine is the main metabolite of Aciclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent.
    9-Carboxymethoxymethylguanine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W178868S
    Lodoxamide impurity 1-d5
    Lodoxamide impurity 1-d5 is deuterium labeled n-Ethyl-2-hydroxyacetamide.
    Lodoxamide impurity 1-d<sub>5</sub>
  • HY-13056R
    SMND-309 (Standard)
    Dimepiperate (Standard) is the analytical standard of Dimepiperate. This product is intended for research and analytical applications. Dimepiperate (MY 93) is a thiocarbamate (TC) pesticide. Dimepiperate has potential off-targets effect for the inhibition of ABHD6.
    SMND-309 (Standard)
  • HY-131270
    Febuxostat impurity 8
    Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.
    Febuxostat impurity 8
  • HY-114656
    Dihydro-PGF1α
    Dihydro-PGF1α is a potential metabolite of PGF1α.
    Dihydro-PGF1α
  • HY-Z0081
    2S,4R-Sacubitril
    2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
    2S,4R-Sacubitril
  • HY-116787
    5-Hydroxythiabendazole
    5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure.
    5-Hydroxythiabendazole
Cat. No. Product Name / Synonyms Application Reactivity