2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

PDF 3.95 MB

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-143938S
    Cyclobenzaprine impurity 2-d3 hydrochloride
    Cyclobenzaprine impurity 2-d3 (hydrochloride) is the deuterium labeled Cyclobenzaprine impurity 2 hydrochloride.
    Cyclobenzaprine impurity 2-d<sub>3</sub> hydrochloride
  • HY-172560
    6β-Oxycodol N-oxide
    6β-Oxycodol N-oxide is an opioid derivative and a metabolite of Oxycodone, which can be detected in urine.
    6β-Oxycodol N-oxide
  • HY-171732
    FANFT
    FANFT is an orally active and potent uroepithelial carcinogen. FANFT is metabolized to ANFT in vivo, which induces gene mutations and malignant cell transformation. FANFT efficiently induces bladder tumors in mice.
    FANFT
  • HY-120190
    Citreoindole
    Citreoindole is a diketopiperazine metabolite isolated from a hybrid cell fusion of two strains of P. citreovirde that is cytotoxic in vitro against HeLa cells at 8.4 μM.
    Citreoindole
  • HY-122317
    Menthol glucuronide
    Menthol glucuronide, a metabolite of Menthol (HY-N1369), is a plasma and urine biomarker of acute Menthol inhalation.
    Menthol glucuronide
  • HY-W766163
    7-Hydroxy coumarin glucuronide-d5 sodium
    7-Hydroxy coumarin glucuronide-d5 sodium is the deuterium labeled 7-Hydroxy coumarin glucuronide sodium (HY-120201). 7-Hydroxy coumarin glucuronide sodium is a benzopyrone and a metabolite of 7-hydroxy coumarin.
    7-Hydroxy coumarin glucuronide-d<sub>5</sub> sodium
  • HY-12767S
    4-Hydroxyphenyl Carvedilol-d5
    4-Hydroxyphenyl Carvedilol-d5 is the deuterium labeled 4-Hydroxyphenyl Carvedilol.
    4-Hydroxyphenyl Carvedilol-d<sub>5</sub>
  • HY-151930S1
    8′-Hydroxy ABA-d2
    8′-Hydroxy ABA-d2 is the deuterium labeled 8’-Hydroxy ABA.
    8′-Hydroxy ABA-d<sub>2</sub>
  • HY-106894
    Lufironil
    Lufironil (HOE 077) is a prolyl 4-hydroxylase inhibitor. Lufironil is developed for the research of chronic liver diseases including alcoholic hepatitis and liver cirrhosis.
    Lufironil
  • HY-N15717
    (erythro) 1′,2′-Dihydroxyasarone
    (erythro) 1′,2′-Dihydroxyasarone is a metabolite of Beta-asarone (HY-N1501) and can also be isolated from the roots of Acorus tatarinowii. (erythro) 1′,2′-Dihydroxyasarone can form glucuronic acid conjugates in vivo and be excreted in urine. (erythro) 1′,2′-Dihydroxyasarone can serve as a marker for the metabolism and toxic risk assessment of Beta-asarone.
    (erythro) 1′,2′-Dihydroxyasarone
  • HY-164949
    Ribociclib acetate
    Ribociclib acetate is a degradation product of Ribociclib (HY-15777) under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic.
    Ribociclib acetate
  • HY-W011956R
    6-Hydroxymelatonin (Standard)
    6-Hydroxymelatonin (Standard) is the analytical standard of 6-Hydroxymelatonin. This product is intended for research and analytical applications. 6-Hydroxymelatonin is a primary metabolic of Melatonin, which is metabolized by cytochrome P450 (CYP) 1A2.
    6-Hydroxymelatonin (Standard)
  • HY-143961S
    Givinostat impurity 5-d4
    Givinostat impurity 5-d4 is the deuterium labeled Givinostat impurity 5.
    Givinostat impurity 5-d<sub>4</sub>
  • HY-143977S
    Loxapine impurity 3-d8 iodide
    Loxapine impurity 3-d8 (iodide) is the deuterium labeled Loxapine impurity 3 iodide.
    Loxapine impurity 3-d<sub>8</sub> iodide
  • HY-131269
    Febuxostat impurity 7
    		98.18%
    Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.
    Febuxostat impurity 7
  • HY-135388
    ent-Ezetimibe
    ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
    ent-Ezetimibe
  • HY-19570A
    NSC 15830 hydrochloride
    NSC 15830 (S-(1,2-Dichlorovinyl)-L-cysteine) hydrochloride is a nephrotoxin and metabolite of trichloroethylene. NSC 15830 hydrochloride inhibits pathogen-stimulated TNF-α.
    NSC 15830 hydrochloride
  • HY-135372
    Descarbamoyl cefuroxime
    Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics.
    Descarbamoyl cefuroxime
  • HY-W711177
    Mono(7-carboxy-2-methyloctyl) phthalate-d4
    Mono(7-carboxy-2-methyloctyl) phthalate-d4 (MCNP-d4) is the deuterium labeled Mono(7-carboxy-2-methyloctyl) phthalate (HY-133679). Mono(7-carboxy-2-methyloctyl) phthalate (MCNP) is a metabolite of Di-decyl phthalate (DDP).
    Mono(7-carboxy-2-methyloctyl) phthalate-d<sub>4</sub>
  • HY-G0003S1
    Iloperidone metabolite Hydroxy Iloperidone-d3
    Iloperidone metabolite Hydroxy Iloperidone-d3 is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone.
    Iloperidone metabolite Hydroxy Iloperidone-d<sub>3</sub>
Cat. No. Product Name / Synonyms Application Reactivity